RecA-DNA helical complexes in genetic recombination.
نویسندگان
چکیده
RecA protein (product of the recA gene), without the help of any other protein, is able in an ATP-dependent reaction to mediate the entire recombination process including the search for homology, homologous pairing and strand transfer (for a review see Radding, 1982; Howard-Flanders et al., 1984b). In this short review, we describe RecA-DNA complexes and how formation of a RecA complex with single-stranded DNA leads to a complete strandexchange reaction between double-stranded linear DNA molecule and homologous to it single-stranded circular DNA molecule.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 14 2 شماره
صفحات -
تاریخ انتشار 1986